在患有间歇性肺部疾病的受试者中,骨肌肉强度的特征
Thatielle Garcia1, Leandro Cruz Mantoani1, Humberto Silva1
1Department of Physiotherapy, Laboratory of Research in respiratory physiotherapy (LFIP), Londrina State University, Londrina, Brazil.
Archives of physical medicine and rehabilitation
|January 25, 2024
概括
患有间歇性肺部疾病 (ILD) 的成年人经历了显著的肌肉衰弱,上肢和下肢的力量减少. 这种肌肉软弱会影响20-46%的ILD患者,特别影响下肢肌肉.
科学领域:
- 肺部医学 肺部医学
- 神经肌肉生理学 神经肌肉生理学
背景情况:
- 间歇性肺部疾病 (ILD) 是一组慢性呼吸系统疾病.
- 肌肉衰弱是慢性疾病的潜在并发症,但其在ILDs中的流行率尚未确定.
研究的目的:
- 为了比较成年人与ILD的肌肉力量与健康个体.
- 为了确定成年人与ILDs肌肉衰弱的患病率.
主要方法:
- 一项横截面研究,将112名患有ILD的成年人与64名健康对照人进行比较.
- 肌肉强度测量是使用上肢和下肢肌肉的最大同位数自愿收缩来测量.
- 肌肉软弱被定义为从对照组数据中得出的正常的下限以下的强度.
主要成果:
- 与对照组相比,在所有评估的肌肉群中,患有ILD的成年人表现出明显较低的肌肉强度 (p≤.001).
- 在ILD患者中,肌肉衰弱的患病率从16% (三头) 到46% (四头) 之间.
- 下肢肌肉,特别是四头肌,表现出最多的弱点.
结论:
- 患有ILD的成年人具有普遍的外周肌肉力量减少.
- 肌肉软弱在ILD患者中很常见,下肢肌肉的患病率更高.
- 这些发现凸显了ILDs对肌肉功能的系统影响.
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