调查焦虑障碍与心率变化之间的关联,测量时使用可穿戴设备进行测量
Julia Tomasi1, Clement C Zai2, Gwyneth Zai3
1Tanenbaum Centre for Pharmacogenetics, Molecular Brain Science Department, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada.
Journal of affective disorders
|January 25, 2024
概括
这项研究发现,患有焦虑症的个体心率变化率 (HRV) 较低,这是迷走神经的衡量标准.
科学领域:
- 精神病学和行为医学
- 心脏病学 心脏病学
- 生物医学工程 生物医学工程
背景情况:
- 阴道中介心率变化 (HRV) 的减少与焦虑症 (AD) 有关.
- 以前的研究表明存在关联,但远程,基于可穿戴设备的研究较少见.
研究的目的:
- 用可穿戴设备和远程研究设计重新评估HRV和AD之间的关联.
- 探索HRV与焦虑特征,混因素和抗抑郁药物的关系.
主要方法:
- 240名参与者 (120名阿尔茨海默病患者,120名对照患者) 通过手腕带在家进行HRV评估,远程监测.
- 分析对各组之间的HRV进行了比较,检查了与焦虑特征和混因子的关联,并评估了抗抑郁药物的作用,按祖先分层.
主要成果:
- 患有AD的患者在欧洲亚样本中的阴道介导HRV明显低于对照组,整体样本的趋势.
- 在欧洲人中,HRV与焦虑症状严重程度 (HAM-A) 有关,但与抗抑郁药的使用无关.
- 年龄是影响HRV的唯一显著的混因素.
结论:
- 通过阴道介导的HRV降低在ADS患者中得到确认.
- 低HRV可能表明焦虑的亚型,以身体症状为特征.
- 可穿戴技术可用于远程HRV监测,支持其在AD风险评估中的临床实用性.
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