在内血管血栓切除术后"幽灵心脏病核心"的患病率
Johanna M Ospel1,2, Nathaniel Rex2,3, Leon Rinkel2,4
1From the Department of Diagnostic Imaging (J.M.O., M.D.H., M.G.), University of Calgary, Calgary, Alberta, Canada.
AJNR. American journal of neuroradiology
|January 25, 2024
概括
计算机断层扫描输液 (CTP) 在急性缺血性中风患者中经常高估了心脏病核心大小. 这种"幽灵核心"现象在年轻患者中很常见,这些患者完全重新治疗,症状发作时间很短,成像时间很短.
科学领域:
- 神经成像是一种神经成像.
- 脑卒中成像 脑卒中成像
- 大脑输液,大脑输液
背景情况:
- 基线计算机断层扫描输液 (CTP) 可以高估心脏病核心大小,这种现象被称为"幽灵核心".
- 准确的心脏病核心体积评估对于急性缺血性中风治疗决策至关重要.
研究的目的:
- 为了确定CTP的频率,与24小时成像相比,高估了心脏病核心体积.
- 为了确定与"幽灵核心"现象相关的患者特征.
主要方法:
- 从ESCAPE-NA1试验中分析了421名患者的基线CTP和24小时后续成像.
- "幽灵核心"的定义是CTP核心体积超过24小时心脏病发作体积>10毫升.
- 多变量后勤回归用于评估临床特征和幽灵核心之间的关联.
主要成果:
- 在11.2%的患者 (n=47) 中观察到"幽灵核心">10毫升.
- 幽灵心脏病发作中位数体积为13.4毫升.
- 较年轻的年龄,完整的再通道化,以及从最后一个已知井到CT的时间较短与幽灵核心有关.
结论:
- 在大约十分之一的急性缺血性中风患者中,CTP高估了心脏病核心大小.
- "幽灵核心"现象在年轻的患者中尤其普遍,这些患者实现了完全的再通道化,并有更短的缺血持续时间.
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