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Updated: Jul 4, 2025

Enhancement of Apoptotic and Autophagic Induction by a Novel Synthetic C-1 Analogue of 7-deoxypancratistatin in Human Breast Adenocarcinoma and Neuroblastoma Cells with Tamoxifen
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二氧化纳米颗粒通过TM4细胞中的ROS-Ca2+-p38/AKT/mTOR通路诱导细胞亡

Qianqian Wang1, Yaqian Yang2, Pengfei Li1

  • 1Department of Preventive Medicine/the Key Laboratory for Prevention and Control of Emerging Infectious Diseases and Public Health Security, the Xinjiang Production and Construction Corps, School of Medicine, Shihezi University, Shihezi, China.

Journal of applied toxicology : JAT
|January 25, 2024
PubMed
概括

二氧化纳米颗粒 (TiO2 NPs) 通过增加活性氧物种 (ROS) 和 (Ca2+) 水平,诱导TM4细胞的亡. 这种过量的激活了p38/AKT/mTOR通路,导致细胞死亡.

关键词:
在Ca2+中.在TM4细胞中,灭症 (apoptosis) 是一种死亡的过程.p38/AKT/mTOR路径中的一个.二氧化纳米颗粒的二氧化.

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