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前新生细胞从最初就切换到华堡代谢,暴露了针对性消除的多个漏洞

Henna Myllymäki1,2, Lisa Kelly1, Abigail M Elliot1,3

  • 1Centre for Inflammation Research, Institute for Regeneration and Repair, The University of Edinburgh, Edinburgh, EH16 4UU, UK.

Oncogenesis
|January 25, 2024
PubMed
概括

癌细胞在发育早期表现出改变的能量代谢. 基因激活触发了增强的葡萄糖分解和受损的氧化酸化 (OXPHOS),为 preneoplastic 细胞消除提供了潜在的治疗点.

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