一项比较研究评估营养药在口腔白血病治疗效果: - - 一个随机的临床轨道
Tanveer Ahmad1,2, Imran Khan1,3, Asia Sultana4
1Department of Biosciences, Faculty of Natural Sciences, Faculty of Dentistry, Jamia Millia Islamia, New Delhi, India.
National journal of maxillofacial surgery
|January 26, 2024
概括
这项研究发现,单独或组合使用利科和黄素,可以有效治疗口腔白血病. 组合疗法显示了最高的治愈率,这表明对这种常见的口腔疾病有协同效益.
科学领域:
- 口腔医学是指口腔医学.
- 营养保健品 营养保健品
- 在瘤学瘤学.
背景情况:
- 口腔白血病 (OL) 是一种常见的口腔粘膜疾病,全球患病率为2.6%.
- 它提出了诊断挑战,依赖于视觉检查和触摸.
- OL具有可变的恶性转变率,在全球范围从0.13%到34%,在印度范围从0.13%到10%.
研究的目的:
- 评估单独或联合使用口服库尔库和莱科治疗口服白血病的疗效.
- 在一项随机对照试验中比较这些营养药的治疗效果.
主要方法:
- 这是一项随机对照试验,涉及300名口腔白血病患者.
- 参与者被分配到接受黄素 (500毫克/天),柳科 (4毫克/天) 或两者的组合的组.
- 通过90天的治疗和3个月的随访,通过病变测量和摄影来评估临床反应.
主要成果:
- 库尔库明治疗的治愈率为51%;莱科治疗的治愈率为63%;组合治疗的治愈率为72%.
- 与黄素相比,Lycopene表现出一个更好的个人营养效应.
- 结合疗法在90天后显示出优于单一营养药的结果,与单独的黄素相比,有显著差异.
结论:
- 黄素和莱科是治疗口腔白血病的有效营养药.
- 组合疗法比单个疗法提供更高的疗效.
- 利科是一种有前途的药物,其与黄素的结合需要进一步研究,以管理口腔白血病.
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