在自闭症谱系障碍中的皮质-状回路:平衡行为
1Chobanian and Avedisian School of Medicine, Boston University, Boston, MA, United States.
Frontiers in cellular neuroscience
|January 26, 2024
概括
基底质的直接和间接途径影响社会行为和重复行为. 本综述探讨了它们在神经类型个体和自闭症谱系障碍中的作用.
科学领域:
- 神经科学是一个神经科学.
- 行为神经科学 行为神经科学
- 计算神经科学是一种神经科学.
背景情况:
- 基底腺节对于运动控制和奖励处理至关重要.
- 它们显著影响社会和重复性行为.
- 基底腺节通过直接和间接的途径调节皮质活动.
研究的目的:
- 审查直接和间接途径的不同角色.
- 检查这些途径对社会和重复性行为的贡献.
- 为了比较神经类型与自闭症谱系障碍 (ASD) 条件中的途径功能.
主要方法:
- 关于基底腺路径研究的文献综述.
- 分析神经成像和行为数据.
- 跨神经类型和自闭症群体的比较分析.
主要成果:
- 直接途径与行动启动和奖励寻求有关.
- 间接途径与行动抑制和习惯形成有关.
- 这些路径的变化与ASD中出现的重复行为有关.
结论:
- 直接和间接的途径差别调节社会和重复行为.
- 了解这些途径为神经发育障碍 (如ASD) 提供了洞察力.
- 准基底腺路径可能对行为变化具有治疗潜力.
相关概念视频
Autism Spectrum Disorder
96
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
96
Modeling in Therapy
79
Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
79
Operant Conditioning Intervention
57
Operant conditioning serves as a foundational principle in therapeutic interventions aimed at modifying maladaptive behaviors. Central to this approach is the notion that behaviors, both adaptive and maladaptive, are learned through reinforcement. By analyzing the environmental factors that reinforce problematic behaviors, clinicians can design interventions to weaken these reinforcements and replace maladaptive behaviors with healthier alternatives.
In operant conditioning, behaviors that are...
In operant conditioning, behaviors that are...
57
Indirect Motor Pathways
1.5K
The indirect motor or extrapyramidal pathways originate in the brainstem, the lower portion of the brain that connects it to the spinal cord. They consist of several distinct tracts, each with specialized functions. The four main tracts of the indirect motor pathways are the vestibulospinal tract, the reticulospinal tract, the tectospinal tract, and the rubrospinal tract.
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
The vestibulospinal tract originates in the vestibular nuclei of the brainstem. The vestibular system detects changes in...
1.5K


