转激素由微生物上调调节,并作为免疫的负调节剂,诱导肠道免疫耐受性

Xiaopeng Tang1,2, Mingqian Fang1, Ruomei Cheng1

  • 1Engineering Laboratory of Peptides of Chinese Academy of Sciences, Key Laboratory of Bioactive Peptides of Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, National Resource Center for Non-Human Primates, National Research Facility for Phenotypic & Genetic Analysis of Model Animals (Primate Facility), and Sino-African Joint Research Center, New Cornerstone Science Institute, Kunming Institute of Zoology, the Chinese Academy of Sciences, No.17 Longxin Road, Kunming, Yunnan, 650201, China.

PubMed
概括

共生微生物促进肠道转移素,一种免疫抑制剂,通过抑制模式识别受体信号传递,促进肠道耐受性. 这种机制对于维持肠道平衡和免疫耐受性至关重要.

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