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面对情绪:基于fMRI的实时神经反使用动态情绪面部来调节杏仁体活动

Apurva Watve¹, Amelie Haugg², Nada Frei²

¹Department of Psychiatry, Psychotherapy, and Psychosomatics, Psychiatric University Hospital, University of Zürich, Zürich, Switzerland.

Frontiers in neuroscience

|January 26, 2024

概括

这项研究探讨了使用情感面部来调节杏仁核活动的新型神经反. 在恐惧-下降组中实现了杏仁体下调,这表明治疗情感障碍的潜力.

科学领域:

神经科学是一个神经科学.
精神病学是一个精神病学.
认知科学认知科学

背景情况:

不适应的杏仁体功能与情绪调节缺陷有关.
实时fMRI神经反显示了调节杏仁体活动的前景.
标准的神经反经常使用抽象的表征,限制了自然主义的应用.

研究的目的:

为了研究一种新的神经反范式,使用自然主义的情感面孔.
评估使用面部表情强度变化来调节杏仁核活动的可行性.
用情感面部反来探索杏仁体的双向调节.

主要方法:

64名健康参与者完成了一次实时fMRI神经反会.
参与者被分配到快乐的,快乐的,恐惧的或恐惧的小组.
反涉及根据杏仁体活动调整情绪面部强度.

主要成果:

在恐惧-下降组中观察到显著的杏仁体下调.
快乐或快乐的群体中没有发生显著的杏仁体变化.
在快乐的群体中,FFA与杏仁体之间的有效连接性增加,而在恐惧的群体中则下降.

结论:

情绪面部神经反范式是可行的,可以定制用于情绪处理.
通过抑制性mOFC机制观察到杏仁体下调.
需要进一步的研究来改善学习成功和行为结果.

关键词:

阿米格达拉的桃体动态的面孔是动态的面孔情绪调节情绪调节通过神经反,可以获得神经反.实时 fMRI 的时间.

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