越南早产婴儿低血糖的决定因素:一个案例对照研究
Rang N Nguyen1, Tuong M Tran1, Ly Lien H Le2
1Department of Pediatrics, Can Tho University of Medicine and Pharmacy, Can Tho, VNM.
Cureus
|January 26, 2024
概括
孕期糖尿病 (GDM) 和过度的孕期体重增加是早产婴儿低血糖的关键危险因素. 这些情况,以及妊娠高血压,显著增加新生儿低血糖的可能性.
科学领域:
- 新生儿医学 新生儿医学
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 过早出生的婴儿面临低血糖症的更高风险,需要早期检测和干预,以防止神经损伤.
- 了解脆弱人群中的特定风险因素,例如越南的早产儿,对于有针对性的预防策略至关重要.
研究的目的:
- 确定越南人口中早产婴儿新生儿低血糖症 (NH) 的主要决定因素.
- 分析在这个特定的人群中导致低血糖的孕产妇和新生儿因素.
主要方法:
- 在越南安妇女儿童医院新生儿重症监护病房进行了一项病例对照研究.
- 低血糖症被定义为血葡萄糖<2.6 mmol/L (47 mg/dL) 产后两个小时.
- 使用双变量和多重逻辑回归分析来确定NH的风险因素.
主要成果:
- 孕期糖尿病 (GDM) 与NH (AOR 3.78,P < 0.001) 有意义地相关.
- 过度的妊娠体重增加 (GWG) 也是NH的重要决定因素 (AOR 2.80,P < 0.026).
- 妊娠高血压和GDM之间的显著相互作用显示出与NH (OR 6.29) 的强烈关联.
结论:
- GDM和过度的GWG被确定为早产婴儿低血糖的重要决定因素.
- 妊娠高血压和GDM的综合作用对NH的风险大大增加.
- 这些发现强调了管理母亲GDM和GWG对于预防早产新生儿低血糖的重要性.
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