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儿童饮食失控与皮层和皮层下大脑结构的改变有关
Alaina L Pearce1, Bari Fuchs1, Shana Adise2
1Department of Nutritional Science, The Pennsylvania State University, University Park, PA, United States.
Frontiers in psychology
|January 26, 2024
概括
经历失控 (LOC) 饮食的儿童表现出明显的脑结构差异. 儿科LOC饮食的这些发现可能表明过度饮食障碍 (BED) 的神经生物学前体.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 儿科精神病学 儿科精神病学
背景情况:
- 儿童饮食失控 (LOC) 是过度饮食障碍 (BED) 的危险因素.
- 儿童LOC饮食的神经生物学基础尚未得到充分理解.
- 之前对BED儿童的研究指出,认知控制和奖励区域的灰质体积发生了变化.
研究的目的:
- 为了研究LOC饮食儿童的大脑结构差异.
- 通过检查LOC饮食儿童的大脑结构来确定BED的潜在神经生物学前体.
- 为了对现有的T1 MPRAGE扫描数据进行二次分析.
主要方法:
- 对五项涉及T1 MPRAGE扫描的研究的二次分析.
- 包括143名7-12岁的儿童;37人报告LOC饮食.
- 检查的灰色物质体积,皮质厚度,化,深度和皮质复杂性,调整为共变量.
主要成果:
- 患有LOC饮食的儿童在右轨道前皮层中表现出较大的灰质体积.
- 观察到右侧准海马回环,左侧CA4/牙状回环和左侧小脑叶VI的灰质体积减少.
- 观察到左前带状皮质和状皮质的深度增加,右岛状皮质的皮质复杂性增加.
结论:
- 患有LOC饮食的儿童表现出结构性大脑差异.
- 这些差异存在于与认知控制和基于奖励的决策相关的大脑区域.
- 研究结果表明,在LOC饮食的儿童中,BED发育的潜在神经生物学标志物.
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