血小板通过急性心肌梗塞后的原受体GPVI调节心脏重塑

Friedrich Reusswig1, Matthias Dille1, E Krüger1

  • 1Department of Vascular- and Endovascular Surgery, University Hospital Düsseldorf, Heinrich-Heine University, Düsseldorf, Germany.

Frontiers in immunology
|January 26, 2024
PubMed
概括

在小鼠中,糖蛋白VI (GPVI) 缺乏改善了心肌梗塞后的心脏重塑,通过减少血小板激活和改变痕原蛋白. 这表明GPVI是改善心脏愈合后缺血性再注射损伤的治疗目标.

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