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在非流行地区的神经沙病症的诊断挑战

Keshari Shrestha¹, B K Kleinschmidt-DeMasters^1,2, D Ryan Ormond¹

¹Department of Neurosurgery, University of Colorado School of Medicine, Aurora, CO, United States.

Frontiers in neurology

|January 26, 2024

概括

在非流行性地区,神经类病 (NS) 的诊断很困难. 这项研究强调了具有挑战性的NS病例,包括罕见的持续质量,强调了诊断时需要保持警的必要性.

科学领域:

神经学神经学
病理学病理学病理学
放射学放射学是一门学科.

背景情况:

神经类病 (NS) 带来了诊断挑战,特别是在流行率低,非流行地区,如美国西南部.
NS可以模仿其他疾病,如脑膜癌,脑膜炎,神经,或结核病.
诊断困难增加,当系统性沙尔科毒症的迹象是缺席或持续质量是存在的.

研究的目的:

审查科罗拉多州的神经类症病例,重点关注初始组织学确认.
识别和分析神经类症的不寻常表现.

主要方法:

从2008年到2019年对"神经沙病"病例进行部门数据库的回顾性搜索.
纳入标准:不寻常的临床/神经成像特征和中枢神经系统 (CNS) 活检作为沙尔科毒症的首次确认.

主要成果:

确定了17例神经类病变;9例最初通过中枢神经系统活检得到证实.
两个不寻常的病例涉及模仿脑膜瘤的长期基质量.
一个病例呈现为纯NS,导致脑膜瘤样病变;另一个病例具有共存的脑膜瘤和NS颗粒瘤.

结论:

具有非典型表现的神经沙丘病在非流行地区带来了重大诊断挑战.
神经学家,神经放射学家和病理学家需要提高意识来诊断不寻常的NS病例.

关键词:

自身免疫性疾病是一种自身免疫性疾病.同时存在的脑膜瘤这是一种神经类化症.这种类型的麻虫是sarcoid.不寻常的呈现方式不寻常的呈现方式

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