阻塞性睡眠呼吸暂停和PD患者视觉幻觉之间的关系:一个多睡眠学研究
Jun Zhu1, Yang Zhao1, Yinyin Jiang1
1Department of Geriatric Neurology, Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing, Jiangsu, China.
Frontiers in neurology
|January 26, 2024
概括
视觉幻觉 (VHs) 和阻塞性睡眠呼吸暂停 (OSA) 在帕金森病中很常见.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 眼科医生 眼科 眼科
背景情况:
- 帕金森病 (PD) 是一种神经退行性疾病.
- 视觉幻觉 (VHs) 和阻塞性睡眠呼吸暂停 (OSA) 是PD中常见的并发症.
- 了解VHs和PD中的OSA之间的相互作用对于患者管理至关重要.
研究的目的:
- 为了确定中国PD患者中VHs和OSA的流行率.
- 在这个人群中探索与VHs和OSA相关的临床特征.
- 为了调查VH和OSA严重程度之间的关系.
主要方法:
- 研究了489名中国PD患者的队列.
- 患者根据VH的存在和严重程度 (小VH,形成的VH) 使用UPDRS和问卷进行分类.
- 进行了多睡眠摄影 (PSG) 来对睡眠进行客观评估,包括呼吸暂停-呼吸暂停指数 (AHI).
主要成果:
- 在29.2%的PD患者中存在VH.
- 随着VH严重程度的增加,OSA的患病率增加 (非幻觉者中的38.7%,形成的VH中为63.3%).
- 病毒性高血压与更长的疾病持续时间,更高的UPDRS得分和更差的睡眠质量有关,其中AHI,N1%,呼吸相关的唤醒和最低的O2独立与病毒性高血压有关.
结论:
- 这项研究证实了中国PD患者中VH和OSA的高患病率.
- 在VHs和PD中OSA严重程度之间存在显著的关联.
- 这些发现强调了在患有VHs的PD患者中进行OSA查的重要性.
更多相关视频
07:54Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
19.8K
04:53Author Spotlight: Traditional Chinese Medicine for Sleep Disorders in Acute COPD — A Safe, Cost-Effective Approach
Published on: October 18, 2024
787
相关概念视频
Sleep Apnea
156
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
The condition is more prevalent among...
156
REM Sleep Behavior Disorder
187
REM Sleep Behavior Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis that normally occurs during the REM phase of sleep. This absence allows individuals to physically act out their dreams, which are often vivid and disturbing. Common behaviors exhibited during episodes include kicking, punching, and yelling. These actions can be dangerous, potentially leading to injuries for the person with RBD or their bed partner.
RBD is significantly associated with...
RBD is significantly associated with...
187
Parkinson's Disease: Treatment
268
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
268
Photoreceptors and Visual Pathways
6.0K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.0K
Parkinson's Disease: Overview
547
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
547
Positive Symptoms Schizophrenia: Hallucinations and Delusions
57
Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
Hallucinations
Hallucinations in...
57
