腹腔内出血的频率及其危险因素
Mohsen Haghshenas-Mojaveri1,2, Forough Alikabranya Omran3, Soraya Khafri4
1Non-Communicable Pediatric Disease Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R. Iran.
Current pediatric reviews
|January 26, 2024
概括
腹腔内出血 (IVH) 在早产儿中很常见,但严重的形式很少见. 风险因素包括低出生体重和早产,而产前皮质类固醇可以降低IVH风险.
科学领域:
- 新生儿神经学 新生儿神经学
- 儿童脑血管疾病 儿童脑血管疾病
- 围产儿医学 围产儿医学
背景情况:
- 腹腔内出血 (IVH) 是早产婴儿中最常见的中风,导致潜在的长期神经缺陷.
- 了解IVH的发病率和风险因素对于改善高风险新生儿的结果至关重要.
研究的目的:
- 在特定的临床环境中确定早产婴儿IVH的频率.
- 确定与此种人群中IVH发生相关的重大风险因素.
主要方法:
- 在第三级新生儿重症监护病房进行了横截面研究.
- 包括没有重大先天性异常的早产婴儿 (<34周怀孕,<1500克出生体重).
- 在生命的第一个星期内进行了大脑超声波,并使用千平方和逻辑回归进行了比较分析.
主要成果:
- 这项研究包括205名早产婴儿,52.1%患有IVH.
- 大多数IVH病例是轻度的 (I级和II级,97.3%),严重的形式 (III级和IV级) 是罕见的 (2.7%).
- 显著的危险因素包括妊娠年龄<28周,出生体重<1000克,阴道分娩,窒息,机械通风,酸性,多巴胺输液和孕产妇发烧/肌炎. 产前皮质类固醇显示具有保护作用 (OR=10.63).
结论:
- 在低出生体重 (<1500g) 的婴儿中,IVH的患病率很高,但严重的等级很少见.
- 高风险的怀孕和特定的新生儿因素与IVH风险增加有显著的相关性.
- 产前使用皮质类固醇似乎是对IVH的保护因素.
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