糖尿病患者肠道微生物组合与微血管并发症之间的关联:系统性审查
Motahareh Hasani1, Zahra Asadi Pilerud2, Atefe Kami3
1Department of Nutrition, School of Health, Golestan University of Medical Sciences, Gorgan, Iran.
Current diabetes reviews
|January 26, 2024
概括
肠道微生物群的改变与糖尿病并发症,如脏病和视网膜病变有关. 调节肠道细菌可能有助于管理这些情况.
科学领域:
- 微生物学 微生物学
- 内分泌学 在内分泌学.
- 腎臟病學 (nephrology) 是一種醫學.
背景情况:
- 糖尿病是一种复杂的慢性疾病,与微血管并发症有关.
- 肠道微生物群失调可以促进炎症,有助于糖尿病的发展及其并发症.
研究的目的:
- 系统地审查糖尿病微血管并发症 (视网膜病变,神经病变,病变) 与肠道微生物群组成之间的关联.
主要方法:
- 在PubMed,Scopus和ISI Web of Science进行了系统的文献搜索.
- 数据提取和质量评估由两位独立审查员使用纽卡斯尔-太华尺度进行.
主要成果:
- 包括19篇文章,病是研究最多的并发症.
- 在神经病变患者中观察到肠道微生物群的变化,包括增加的Fusobacteria和Proteobacteria.
- 视网膜病变与致病性和促炎性细菌的增加有关.
结论:
- 增加的细菌,蛋白质细菌和菌可能会导致糖尿病病,神经病和视网膜病.
- 肠道微生物群失生症在糖尿病并发症中起着不利的作用.
- 微生物群评估和调制可能是未来预防和管理糖尿病相关并发症的策略.
相关概念视频
Diabetes: Symptoms, Diagnosis, and Complications
544
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
544
Pathophysiology of Diabetes
940
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
940


