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在初级裂修复失败后,患有1型喉裂的儿童中,上食道关节功能障碍
Corey Baker1, Casey Silvernale2, Christopher Hartnick3
1Pediatric Gastroenterology, Hepatology and Nutrition, Connecticut Children, Hartford, CT 06106, USA.
Biomolecules
|January 26, 2024
概括
患有1型喉裂的儿童往往有吞问题. 这项研究发现,这些儿童的上食道 (UES) 压力在修复后增加,这表明UES运动功能的变化.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 吞障碍 吞障碍 吞障碍
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 吞功能障碍在患有1型喉裂的儿童中很常见.
- 在初始治疗后,症状可能会持续,暗示潜在的运动异常.
- 了解这些异常对于有效管理至关重要.
研究的目的:
- 为了研究1型喉裂儿童的喉和食道运动功能.
- 在干预后患有持续症状的患者中识别特定的尺度变化.
- 为了比较受影响儿童和健康对照儿童之间的运动动态.
主要方法:
- 对高分辨率食道力测量研究的回顾性分析.
- 纳入标准:小于18岁的儿童患有1型喉裂和经过修复后持续的症状.
- 对照组:年龄相匹配的儿童没有喉异常.
主要成果:
- 患有1型喉裂的儿童显示,食道上 (UES) 的静止压力显著增加.
- 观察到UES吞前后最大压力升高,UES收缩持续时间延长.
- 两组之间没有发现UES残留压力或喉动态的显著差异.
结论:
- 这是第一个在初始修复后确定1型喉裂儿童上食道 (UES) 运动功能的特定变化的研究.
- 这些发现突出了UES高度作为持续吞功能障碍的潜在贡献者.
- 进一步的研究可能会探索针对UES运动异常的有针对性的干预措施.
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