来自GEP NET监控的辐射暴露
Jordan Iannuzzi1, Caitlin T Yeo2, Vicky Parkins1
1Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.
Cancers
|January 26, 2024
概括
对切除的胃肠道胰腺神经内分泌瘤 (GEP NET) 的监测导致显著的辐射暴露. 累积剂量可能会增加二次恶性瘤的风险,促使在GEP NET患者护理中需要辐射最小化策略.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 医学物理 医学物理
背景情况:
- 神经内分泌瘤 (NET) 是具有/神经胺分泌的瘤.
- 手术切除是胃肠瘤网的唯一治愈方法.
- 由于晚期复发,建议对GEP NET进行长期监测.
研究的目的:
- 评估完全切除GEP NET的监视实践中的辐射暴露.
- 分析GEP NET监测中的成像方法和随访时间.
- 在GEP NET随访期间评估累积有效辐射剂量.
主要方法:
- 对已有差异的GEP NET病例 (2005-2020年) 的回顾性队列研究.
- 收集了关于主要瘤位置,成像方式和随访持续时间的数据.
- 用于计算有效辐射剂量的剂量计数据.
主要成果:
- 分析了62个病例和422个监控扫描.
- 截面成像占主导地位 (82%).
- 估计10年平均总有效剂量为106mSv,年平均值为10.62mSv.
结论:
- 对GEP NET的切除后监测结果导致大量的累积辐射剂量.
- 这些剂量在与二次恶性瘤风险相关的范围内.
- 未来的指导方针应该包括在监测期间尽量减少辐射暴露的策略.
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