副甲状腺切除术前双追踪器99m-Technetium (Tc) Pertechnetate和Sestamibi扫描的陷:在初级-甲状腺功能障碍症相关的甲状腺瘤和异位甲状腺组织之间
Mara Carsote1,2, Mihaela Stanciu3, Florina Ligia Popa4
1Department of Endocrinology, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Medicina (Kaunas, Lithuania)
|January 26, 2024
概括
这一案例凸显了原发性甲状腺功能增强症 (PHP) 手术中的成像陷. 术前成像表明有两个副甲状腺瘤,但其中一个是异位甲状腺组织,强调了手术期间的警和PTH监测,以确保成功的副甲状腺切除术.
科学领域:
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
- 医疗成像医学成像
背景情况:
- 初级甲状腺功能障碍症 (PHP) 诊断依赖于和副类激素 (PTH) 水平的升高.
- 副甲状腺手术提供高治愈率,但需要精确的瘤定位.
- 常见的定位方法包括超声波和99m-Technetium sestamibi光学.
研究的目的:
- 呈现PHP病例与异位甲状腺组织的意外手术内发现.
- 讨论术前成像在甲状腺瘤局部化的局限性和潜在的陷.
- 强调在副甲状腺切除术期间进行手术内评估和PTH监测的重要性.
主要方法:
- 一个成年女性被诊断患有PHP的案例研究.
- 使用了超声波,双相99m-Tc基酸盐和塞斯塔米比光学,以及计算机断层扫描来进行手术前的定位.
- 采用手术内PTH测定和即时检查用于组织识别.
主要成果:
- 术前成像一致表明双边下侧甲状腺瘤.
- 术后发现显示出异位甲状腺组织,而不是第二次副甲状腺腺瘤.
- 第一个质量的切割后PTH水平突然下降,促使对第二个质量的进一步调查.
结论:
- 术前成像模式可能会呈现错误的阳性结果,并错误识别子宫外组织.
- 术期间的警,包括PTH监测,对于成功的副甲状腺切除术至关重要.
- 意识到潜在的成像陷,并考虑混合成像,可以提高诊断准确性,同时甲状腺和副甲状腺异常.
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