针切除术与脊柱外注类固醇注射用于腰椎神经激光病的有效性:一个随机控制的实用试点研究
Jin-Hyun Lee1, Sang-Hyun Lee2, Hae Sun Suh3,4,5
1Institute for Integrative Medicine, International St. Mary's Hospital, Catholic Kwandong University, Incheon 22711, Republic of Korea.
Medicina (Kaunas, Lithuania)
|January 26, 2024
概括
针切除术与外围注射类固醇注射 (ESI) 结合,显示出对腰部神经根源病的显著有效性和成本效益. 这项试点研究表明,研究这种联合治疗方法的更大规模试验的可行性.
科学领域:
- 疼痛管理 疼痛管理
- 干预性疼痛医学 干预性疼痛医学
- 综合医学是一个整体医学.
背景情况:
- 脊椎骨干细胞病变通常需要多模式的治疗策略.
- 外周注射类固醇 (ESI) 是一种常见的干预措施,但有些患者表现不够好.
- 针切除术是一种微创的技术,正在作为辅助疗法进行探索.
研究的目的:
- 评估针切除术与ESI结合的临床有效性,成本效益和安全性,用于腰部神经根源病.
- 评估这种综合方法在更大规模研究中的可行性.
主要方法:
- 一个随机的,受控的,实用性的试点研究,涉及50名患有严重腰部神经根部病变的患者.
- 患者接受了单独的ESI (对照) 或针术加ESI (实验).
- 主要结局:奥斯韦斯特里残疾指数 (ODI) 在第4周和第8周的变化. 通过ICUR分析的成本效益.
主要成果:
- 联合针切除+ESI组在第4周的ODI得分显著改善 (p = 0.0021).
- 在第8周的ODI平均变化有利于实验组 (-9.04对比 -4.76).
- 增量成本效益比 (ICUR) 显示了组合治疗的有利成本效益.
结论:
- 针切除术与ESI相结合,在治疗腰部神经根源病的治疗中显示出潜在的临床有效性和成本效益.
- 这些发现支持这种联合疗法的可行性,用于未来更大的临床试验.
- 需要进一步的长期研究来证实这些有希望的结果.
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