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Updated: Jul 4, 2025

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细胞巨乳病毒和怀孕:叙述性审查

Karina Felippe Monezi Pontes^1,2, Luciano Marcondes Machado Nardozza¹, Alberto Borges Peixoto^3,4

¹Department of Obstetrics, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo 04023-900, SP, Brazil.

Journal of clinical medicine

|January 26, 2024

概括

先天性细胞巨乳病毒 (CMV) 感染很常见,但像瓦拉西克洛维尔和甘西克洛维尔这样的新疗法提供了希望. 这一审查有助于决定对孕妇进行普遍查.

科学领域:

孕产妇和胎儿的医学
新生儿科学新生儿科学
传染病传染病传染病

背景情况:

先天性细胞巨乳病毒 (CMV) 感染是全球最常见的先天性病毒感染.
它影响0.7%-1%的活产儿,11%的感染新生儿在出生时表现出症状.
显著的百分比的症状新生儿面临长期的神经后果.

研究的目的:

审查先天性CMV感染的流行病学和治疗方法.
评估最近在预防垂直传播和治疗有症状的新生儿方面的进展.
为决定关于孕妇普遍查方案的决定提供信息.

主要方法:

关于先天性CMV感染的最新研究的文献综述.
对瓦拉西克洛维尔和甘西克洛维尔治疗疗效的分析.
流行病学数据的综合.

主要成果:

瓦拉环 (8克/天) 在预防垂直CMV传播方面表现出有效性.
甘西克洛维尔在治疗症状新生儿的长期后果方面是有效的.
新兴的治疗方法证明了对孕妇普遍查的重新评估是合理的.

结论:

现在可以有效治疗先天性CMV感染.
应根据当地资源和能力考虑为孕妇制定通用查方案.
早期干预可以缓解先天性CMV的严重后果.

关键词:

细胞巨型病毒 (cytomegalovirus) 是一种病毒.怀孕怀孕怀孕怀孕怀孕血清学的血清学传输传输传输传输传输传输治疗治疗治疗治疗治疗治疗

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