全球皮肤菌感染:发病率的增加和相关的抗真菌耐药性
Caroline Kruithoff1, Ahmed Gamal2, Thomas S McCormick2
1Heritage College of Osteopathic Medicine, Ohio University, Cleveland, OH 44122, USA.
Life (Basel, Switzerland)
|January 26, 2024
概括
表面的真菌感染正在增加,像Trichophyton indotineae这样的物种出现抗真菌耐药性,这对健康构成重大挑战. 抗真菌敏感性测试对于有效治疗这些耐药性感染至关重要.
科学领域:
- 医学真菌学 医学真菌学
- 传染性疾病 传染性疾病
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 在全球范围内,表面的真菌感染正在增加.
- 皮肤植物的抗真菌耐药性,如Trichophyton rubrum和Trichophyton mentagrophytes,是一个越来越令人担忧的问题.
- 具有高抗特比纳耐药性的Trichophyton indotineae的出现使治疗复杂化.
研究的目的:
- 突出表面真菌感染中抗真菌耐药性的挑战.
- 强调需要超越传统技术的先进诊断方法.
- 倡导在临床实践中进行抗真菌敏感性测试.
主要方法:
- 审查当前关于皮肤菌感染和抗真菌耐药性的文献.
- 分析新兴物种及其耐药性概况.
- 讨论诊断方法和治疗策略.
主要成果:
- 皮肤植物,包括Trichophyton rubrum和Trichophyton mentagrophytes,显示出越来越多的抗真菌耐药性.
- 三植物Indotineae对Terbinafine,一种主要的抗真菌治疗,表现出显著的耐药性.
- 分子诊断是必要的,以准确识别致病原体.
结论:
- 表面真菌菌中的抗真菌耐药性对全球健康和经济构成负担.
- 使用分子方法进行准确的诊断至关重要.
- 抗真菌敏感性测试对于指导耐药皮肤菌感染的有效治疗至关重要.
关键词:
在T. indotineae的研究中.这种植物是T. mentagrophytes.这就是T. rubrumrumrum.皮肤细胞 (dermatophytes) 是一种细胞.发生率的发生率.表面的真菌感染 表面的真菌感染特尔比纳非因 (terbinafine) 是一种药物.三科菲顿 (Trichophyton) 是一个三科菲顿.更多相关视频
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