慢性病与并发病和碳水化合物代谢的相互作用:一篇评论
Radha Kushwaha1, Pothabathula Seshu Vardhan2, Prem Prakash Kushwaha3
1Centre of Food Technology, University of Allahabad, Allahabad 211002, Uttar Pradesh, India.
Life (Basel, Switzerland)
|January 26, 2024
概括
慢性病 (CKD) 破坏细胞生长,激素平衡和营养,增加疾病风险. 了解这些复杂的代谢转变是有效的CKD管理和向治疗的关键.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 代谢医学是一种代谢医学.
- 身体生理学 身体生理学
背景情况:
- 慢性病 (CKD) 是一个全球性的健康问题,导致显著的生理和代谢变化.
- 慢性瘤会影响细胞生长,荷尔蒙平衡,消耗,营养不良,炎症,氧化压力和心血管健康.
- 遗传,与出生有关的,并发症,代谢,贫血和营养不良的因素与CKD有关.
研究的目的:
- 综合审查CKD对生理和代谢过程的多方面的影响.
- 探索CKD,胰岛素抵抗和葡萄糖不耐受之间的复杂关系.
- 分析CKD对生长激素/IGF轴的影响,消耗,味觉障碍和认知/情感福祉.
主要方法:
- 关于慢性病现有研究的综合文献综述.
- 对CKD患者的生理和代谢变化的分析.
- 检查CKD,炎症,氧化应激和心血管疾病之间的相互作用.
主要成果:
- 慢性瘤显著影响细胞生长平衡,荷尔蒙平衡和营养状况,导致高达75%的ESRD患者浪费.
- 胰岛素抵抗和异常在CKD中很普遍,有助于导致葡萄糖不耐受,关于因果关系的争论仍在进行中.
- 在CKD中观察到生长激素/IGF轴的干扰,味觉障碍以及对认知功能和内皮功能的影响.
结论:
- 慢性瘤引发复杂的生理和代谢障碍,包括荷尔蒙失衡,消耗和改变味觉.
- 慢性瘤和胰岛素抵抗之间的关系是复杂的,影响葡萄糖代谢和整体健康.
- 饮食干预对于治疗CKD至关重要,需要对其对患者福祉的多方面的影响有细微的了解.
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