牛奶:对人类健康有好处? 欧米克斯工具和精密营养对于乳糖不耐症管理的精密营养
Giovanni Pratelli1, Bartolo Tamburini2,3, Giusto Davide Badami3
1Department of Biomedicine, Neurosciences and Advanced Diagnostics (BIND), Institute of Biochemistry, University of Palermo, 90127 Palermo, Italy.
Nutrients
|January 26, 2024
概括
个性化营养,整合omics数据,为乳糖不耐症 (LI) 和牛奶蛋白过敏 (CMPA) 提供量身定制的策略. 这种方法超越了"一个尺寸适合所有人",以改善患者的生活质量和健康结果.
科学领域:
- 营养科学 营养科学
- 基因组学就是基因组学.
- 代谢学 代谢学 代谢学
背景情况:
- 乳糖不耐症 (LI) 和牛奶蛋白过敏 (CMPA) 影响全球个体,需要不同的管理策略.
- 目前的方法可能导致误诊,不良反应或不必要的饮食限制,特别是在婴儿中.
- 奥米克技术提供了对营养物体相互作用的洞察,从遗传学到代谢物.
研究的目的:
- 倡导从普遍的饮食建议转向个性化营养 (PN) 策略.
- 突出将omics数据与临床和微生物群概况整合为量身定制的营养的作用.
- 为满足患有LI和CMPA的个体的特殊需求.
主要方法:
- 利用omics技术 (基因组学,蛋白质组学,代谢组学) 来了解个体对营养素的反应.
- 整合遗传因素,微生物群概况和代谢物数据.
- 考虑个别的乳糖耐受性值和营养需求.
主要成果:
- 基于全面的生物数据来识别不同的单个队列.
- 开发个性化的营养计划,以满足特定的饮食需求和容忍度.
- 有可能改善LI患者的生活质量,减少相关的焦虑和抑郁.
结论:
- 科学界建议用个性化的方法取代"适合所有人"的营养.
- 整合营养基因数据,临床参数和微生物群概况是有效的个性化营养的关键.
- 量身定制的营养策略可以显著有利于患有LI和CMPA的个体,提高福祉和健康结果.
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