聚酸口水中的石榴提取物减少了质去矿化
Ana Paula Miranda Vieira1, Marcelle Danelon2, Gabriela Lopes Fernandes1
1Graduate Program of Dental Science, São Paulo State University (UNESP), School of Dentistry, Araçatuba, Brazil.
Clinical oral investigations
|January 26, 2024
概括
石榴皮提取物 (PPE) 用三甲酸 (TMP) 和化物 (F) 的口水有效防止牙去矿化. 与商业口水相比,这种新型配方还显示出较低的刺激潜力.
科学领域:
- 牙科研究 牙科研究
- 口腔健康 口腔健康
- 材料科学 是一种材料科学.
背景情况:
- 牙损仍然是一个重要的全球健康问题.
- 口水通常用于口腔卫生和空预防.
- 寻求新的成分来增强抗脱矿物质的特性并减少刺激.
研究的目的:
- 评估含有石榴皮提取物 (PPE),三甲酸 (TMP) 和化物 (F) 的口水的抗脱矿作用.
- 评估这种新型口水配方的刺激潜力.
- 为了比较其有效性和安全性与商业口水和控制解决方案.
主要方法:
- 一个现场双盲交叉研究,12名志愿者使用面膜块.
- 应用了心脏病发作挑战,并在暴露于不同口水配方 (ETF,TF,水,商业口水) 后分析了质/生物膜特性.
- 使用ex vivo蛋胆 ?? 膜试验来评估刺激潜力.
主要成果:
- 在防止脱矿化方面,ETF配方 (PPE + TMP + F) 最有效.
- 在乳液和生物膜中,ETF显示和的含量较高,细胞外多糖的含量较低.
- ETF显示出最小的刺激 (轻微的红色),而商业口水导致高血和出血.
结论:
- 将PPE与TMP和F结合起来,可以显著增强抗脱矿性质的特性.
- 与商业口水相比,ETF口水配方的刺激潜力较低.
- 这种无酒精的ETF口水是高病风险患者的有希望的替代品.
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