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Updated: Jul 4, 2025

Nanomechanics of Drug-target Interactions and Antibacterial Resistance Detection
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Nanomechanics of Drug-target Interactions and Antibacterial Resistance Detection

Published on: October 25, 2013

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范科米辛的晶体结构与抗性决定剂D-氨酸-D-氨酸结合

Jee Hoon Park1, Rachel E Reviello1, Patrick J Loll1

  • 1Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, PA 19102, USA.

IUCrJ
|January 26, 2024
PubMed
概括

肠球菌中万科素耐药性是一个日益严重的问题. 了解万科米辛如何在分子水平上与耐药标结合,如D-alanine-D-serine,是开发新抗生素的关键.

关键词:
抗生素耐药性 抗生素耐药性抗生素 抗生素是一种抗生素.发现药物的发现.大分子机器是什么?分子识别分子识别这是一个超分子组件.这就是Vancomycin.抗万科胺素的肠球菌.

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相关概念视频

Conserved Binding Sites01:49

Conserved Binding Sites

Many proteins’ biological role depends on their interactions with their ligands, small molecules that bind to specific locations on the protein known as ligand-binding sites. Ligand-binding sites are often conserved among homologous proteins as these sites are critical for protein function.
Binding sites are often located in large pockets, and if their location on a protein’s surface is unknown, it can be predicted using various approaches. The energetic method computationally...
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