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Updated: Jul 4, 2025

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暴露于[a]烯会通过调节ERβ介导的LINC02977转录来影响结直肠癌的易感性

Shuai Ben1, Shuwei Li2, Dongying Gu3

  • 1Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, School of Public Health, Nanjing Medical University, Nanjing 211166, China; Department of Genetic Toxicology, The Key Laboratory of Modern Toxicology of Ministry of Education, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211166, China; Department of Ophthalmology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200080, China.

Environment international
|January 26, 2024
PubMed
概括

多环芳 (PAH),如[a]二烯,通过影响雌激素受体β (ERβ) 与雌激醇不同,增加结直肠癌 (CRC) 风险. 准ERβ可能会提供新的CRC预防和治疗策略.

关键词:
子[a]二烯是一种二烯.结肠直肠癌是一种癌症.雌激素受体β受体是什么遗传变体的遗传变体多环芳香碳化合物 多环芳香碳化合物

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