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Updated: Jul 4, 2025

GC-based Detection of Aldononitrile Acetate Derivatized Glucosamine and Muramic Acid for Microbial Residue Determination in Soil
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使用混合模式染色学和紫外线检测来量化活性药物成分中的残留有机

Louis R Redfern1

  • 1Analytical Research and Development, Small Molecule CMC Development, AbbVie, Inc., 1 North Waukegan Road, North Chicago, IL 60064, USA.

Journal of chromatography. A
|January 26, 2024
PubMed
概括

使用混合模式色谱的新型HPLC方法有效量化了活性药物成分 (API) 中的有机基,如伊米达和1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU). 这种方法为质量控制提供了更好的保留,灵敏度和稳定性.

关键词:
方法开发 方法开发混合模式色谱学混合模式色谱学有机基 有机基.药品制造业 药品制造业 药品制造业 药品制造业

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