系统性并发症对玻璃眼的长期影响 药物坚持
1Department of Ophthalmology (C.H.H.), National Taiwan University Hospital, Taipei, Taiwan; Institute of Public Health, School of Medicine (C.H.H., C.P.), National Yang Ming Chiao Tung University, Taipei, Taiwan.
American journal of ophthalmology
|January 26, 2024
概括
系统性并发症显著减少长期坚持青光眼药物治疗,特别是多种健康状况. 这突出了在复杂患者病例中有效治疗眼的潜在障碍.
科学领域:
- 眼科医生 眼科 眼科
- 公共卫生 公共卫生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 坚持服用青光眼药物对于预防视力丧失至关重要.
- 系统性并发症可能会影响患者管理多种慢性疾病的能力,可能会影响对青光眼治疗的坚持.
研究的目的:
- 为了研究系统性并发症和青光眼药物坚持之间的联系.
- 确定伴随性疾病的数量和青光眼诊断后的时间是否会影响坚持水平.
主要方法:
- 一项基于人口的队列研究,使用台湾国家医疗保险索赔数据.
- 纳入50408名新诊断患有青光眼的患者,随访5年.
- 通过Deyo-Charlson并发症指数评估并通过药物持有率 (MPR) 评估依从性.
主要成果:
- 患有并发症的患者最初表现出更高的坚持,但在诊断后的4年和5年显著下降.
- 随着越来越多的并发性疾病,对青光眼药物的坚持逐渐下降.
- 患有四种或以上并发症的患者在第四年和第五年分别减少了6.4%和11.8%的坚持.
结论:
- 系统性并发症可以将长期的青光眼药物坚持率降低高达12%.
- 管理多种慢性疾病的负担增加可能会导致对青光眼治疗的优先级降低,特别是考虑到其往往无症状的性质.
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