大脑麻的成年人之间的并发症集群:潜伏类分析
Aleda M Leis1, Edward A Hurvitz2, Daniel G Whitney3
1Epidemiology Department, School of Public Health, University of Michigan, Ann Arbor, Michigan.
American journal of preventive medicine
|January 26, 2024
概括
患有脑的成年人在一生中面临着不同的多病态概况. 这些模式,从低发病率到复杂的疾病,与所有年龄组的死亡风险增加有关.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 神经学 神经学
背景情况:
- 大人脑 (CP) 患有早期多发症的风险更高.
- 了解特定的多发病概况及其对CP成年期死亡率的影响至关重要.
研究的目的:
- 在大脑麻的成年人中识别不同的多发病概况.
- 调查这些多发病概况与不同成年年龄组的死亡率之间的关联.
主要方法:
- 使用20%的医疗保险数据库 (2008-2019) 进行回顾性队列研究.
- 隐藏类分析用于确定CP的年轻 (18-39岁),中年 (40-64岁) 和老年 (≥65岁) 成人的多病态模式.
- 从2008-2010年确定并发症 (由ICD-9代码定义的30种);到2019年对死亡率进行随访.
主要成果:
- 出现了三个一致的多发病概况:低发病率,神经多发病率和复杂多发病率.
- 根据年龄而异的第四个概况:精神健康障碍 (年轻),高血压 (中等) 和高血压/关节炎 (老年).
- 除了低发病率外,所有个人资料都与所有年龄组的死亡风险显著增加有关 (HR范围:1.34-5.58,p<0.001).
结论:
- 患有CP的成年人的多发症概况是多样化的,并且在整个生命周期中发生变化.
- 这些独特的个人资料与死亡率有着显著而多样化的关联.
- 研究结果强调,对于患有CP的成年人来说,需要制定特定年龄的治疗策略,以减轻死亡风险.
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