发酵食品:利用它们的潜力调节微生物群-肠-大脑轴,促进心理健康
Ramya Balasubramanian1, Elizabeth Schneider2, Eoin Gunnigle2
1APC Microbiome Ireland, University College Cork, Cork, Ireland; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland; Food Biosciences Department, Teagasc Food Research Centre, Moorepark, Fermoy, P61C996, County Cork, Ireland.
Neuroscience and biobehavioral reviews
|January 26, 2024
概括
含有有益微生物和生物活性物质的发酵食品,通过调节肠道微生物群-大脑轴,显示出改善心理健康的潜力. 需要进一步的研究来了解它们的治疗益处.
科学领域:
- 微生物学 微生物学
- 神经科学是一个神经科学.
- 营养科学 营养科学
背景情况:
- 全食补充剂和精神生物制剂越来越多地研究其对心理健康的益处.
- 微生物群-肠-大脑轴是影响行为和心理健康的关键途径.
- 发酵食品代表着针对这一轴的独特干预.
研究的目的:
- 审查发酵食品的多样性及其对肠道微生物群的影响.
- 要总结如何发酵食品调节肠-大脑通信通路,包括免疫系统.
- 确定知识差距,并为人类研究发酵食品和心理健康提出解决方案.
主要方法:
- 关于发酵食品,肠道微生物群和微生物群-肠道-大脑轴的文献综述研究.
- 对发酵食品的原材料,发酵类型和生物活性成分的分析.
- 检查人类研究设计和调查发酵食品干预措施的挑战.
主要成果:
- 发酵食品含有有益的微生物,代谢物和生物活性物质,可以塑造肠道微生物群的组成.
- 这些成分可以影响肠-大脑通信通路,可能会影响心理健康.
- 现有研究强调了发酵食品干预措施的多样性和研究设计的挑战.
结论:
- 发酵食品为调节微生物群-肠-大脑轴和促进心理健康提供了一个有希望的途径.
- 进一步的精心设计的人体研究对于验证特定发酵食品的治疗潜力至关重要.
- 解决知识差距将促进对发酵食品在心理健康干预中的理解和应用.
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