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hIFITM1的棕化抑制了JEV感染,并有助于BBB稳定

Hao-Wei Chen1, Ya-Ge Zhang1, Wei-Jia Zhang1

  • 1National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, Hubei, China; The Cooperative Innovation Center for Sustainable Pig Production, Huazhong Agricultural University, Wuhan 430070, Hubei, China; Key Laboratory of Preventive Veterinary Medicine in Hubei Province, The Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China.

International journal of biological macromolecules
|January 26, 2024
PubMed
概括

干扰素诱导性跨膜蛋白1 (IFITM1) 限制了日本脑炎病毒 (JEV) 在人类大脑微血管内皮细胞 (hBMEC) 中. IFITM1的棕化对其抗病毒活性和血脑屏障 (BBB) 完整性至关重要.

关键词:
这是BBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBBB如果IFITM1是IFITM1,那么它就是IFITM1.在JEV中,JEV是棕甲基基化是棕甲基化的一种.在 hBMEC 系统中,hBMEC 是

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