Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

5.1K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
5.1K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

A CRX-positive RB1-deficient bone tumour with a retinoblastoma-like DNA methylation profile.

Histopathology·2026
Same author

MUC4-Positive Fibroblastoma: Clinicopathological and Molecular Analysis of 7 Cases.

The American journal of surgical pathology·2026
Same author

Ozonated Olive Oil Attenuates Hepatic Steatosis in Obese db/db Mice: Evidence for Triacylglycerol-derived Ozonides as Key Bioactive Species.

Journal of oleo science·2026
Same author

Durable tumor control with stereotactic radiotherapy and doxorubucin-ifosfamide chemotherapy in primary intracranial sarcoma, <i>DICER1</i>-mutant: a case report.

International cancer conference journal·2026
Same author

BEND2 Immunohistochemistry as a Useful Diagnostic Marker for Astroblastomas With BEND2 Fusion.

The American journal of surgical pathology·2026
Same author

HMGA2 expression in CIC-rearranged sarcoma and other small round/epithelioid cell tumours.

Histopathology·2026

相关实验视频

Updated: Jul 4, 2025

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies
07:15

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies

Published on: July 28, 2020

9.6K

这是CIC重组的肉瘤.

Naohiro Makise1, Akihiko Yoshida2

  • 1Division of Surgical Pathology, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, Chiba-shi, Chiba, 260-8717, Japan.

Surgical pathology clinics
|January 26, 2024
PubMed
概括

CIC重组瘤是一种侵袭性的小圆细胞癌,影响深层软组织. 诊断依赖于特征性组织学和免疫组织化学,尽管对CIC融合的基因检测可能具有挑战性.

科学领域:

  • 在瘤学瘤学.
  • 病理学 病理学 病理学
  • 遗传学 是一个遗传学.

背景情况:

  • CIC重组型肉瘤是一种罕见的,具有攻击性的小圆细胞肉瘤.
  • 它会影响广泛的年龄范围内的深层软组织.
  • 这种肉瘤的预后比尤文肉瘤和化疗抵抗更差.

研究的目的:

  • 为了总结CIC重排肉瘤的关键特征.
  • 突出诊断的挑战和方法.

主要方法:

  • 对组织学和免疫组织化学发现的审查.
  • 讨论CIC融合的遗传检测方法.

主要成果:

  • 特征性组织学包括分片生长,myxoid变化和特定细胞形态.
  • ETV4和WT1核表达是有价值的免疫组织化学标记物.
  • 基因检测,包括下一代测序,可以检测CIC融合,但有局限性,特别是对于CIC::DUX4.

结论:

  • CIC重组的肉瘤呈现出不同的组织学和免疫组织化学特征.
  • 准确的诊断需要整合临床,组织学和分子数据.
关键词:
在 CIC CIC 中,您可以在 CIC CIC 中查看.这是一种CIC重排的肉瘤.DUX4X4 的使用情况在 ETV4 上播放.类似于尤文的肉瘤融合基因是一个融合基因.

更多相关视频

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells
11:42

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells

Published on: April 7, 2017

9.4K
The In ovo CAM-assay as a Xenograft Model for Sarcoma
12:44

The In ovo CAM-assay as a Xenograft Model for Sarcoma

Published on: July 17, 2013

25.5K

相关实验视频

Last Updated: Jul 4, 2025

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies
07:15

A Mouse Model of Incompletely Resected Soft Tissue Sarcoma for Testing Neoadjuvant Therapies

Published on: July 28, 2020

9.6K
Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells
11:42

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells

Published on: April 7, 2017

9.4K
The In ovo CAM-assay as a Xenograft Model for Sarcoma
12:44

The In ovo CAM-assay as a Xenograft Model for Sarcoma

Published on: July 17, 2013

25.5K
  • 在所有CIC聚变类型的敏感分子检测方面仍然存在挑战.