皮肤神经纤维瘤的全球研究趋势:2003年至2022年的图书统计分析
Jiani Wang1, Jie Fu2, Yu Zhou1
1Department of Plastic Surgery, The Third Affiliated Hospital of Anhui Medical University (the First People's Hospital of Hefei), Hefei, China.
概括
图书统计分析显示,人们对皮肤神经纤维瘤 (cNF) 的研究兴趣日益增长,这是一种复杂的遗传性疾病. 新兴的局部疗法和对生活质量的关注显示出改善患者结果的希望.
科学领域:
- 医学遗传学 医学遗传学
- 皮肤病学 皮肤病学
- 图书统计学 图书统计学
背景情况:
- 神经纤维素瘤类型1 (NF1) 是一种常见的遗传性疾病.
- 无法进行手术的皮肤神经纤维瘤 (cNF) 的管理存在挑战.
- 图书统计分析可以揭示cNF的研究趋势和合作.
研究的目的:
- 从2003-2022年分析皮肤神经纤维瘤 (cNF) 的研究格局.
- 确定cNF的关键贡献者,研究趋势和新兴治疗领域.
- 为指导未来的研究和改善NF1.1的患者护理策略.
主要方法:
- 网络科学核心集合 (2003-2022) 的综合文献搜索.
- 使用VOSviewer,CiteSpace和"Bibliometrix"软件包进行图书统计分析.
- 对出版物,合作,共同引用和关键词爆发的评估.
主要成果:
- 分析了来自67个国家的927篇文章,其中美国是研究的领导者.
- 越来越多的研究成果,皮埃尔·沃尔肯斯坦是主要作者,汉堡大学是主要机构.
- 关键的研究趋势包括生活质量评估,基因型-表型相关性和新兴的局部MEK抑制剂.
结论:
- 图书统计分析显示,在过去二十年中,cNF研究显著增加.
- 领先的贡献者和机构已经塑造了这个领域,越来越强调以患者为中心的结果.
- 新兴的局部疗法代表了对cNF管理和患者护理的有希望的进步.
更多相关视频
07:49Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
Published on: April 18, 2025
169
08:57Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
Published on: May 17, 2024
1.9K
相关概念视频
NF-κB-dependent Signaling Pathway
7.4K
The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
NF-κB-dependent Signaling Mechanism
The...
NF-κB-dependent Signaling Mechanism
The...
7.4K
Introduction to Fibroblasts
3.1K
Rudolph Virchow discovered spindle-shaped cells called fibroblasts in 1858. Inactive fibroblasts, called fibrocytes, become activated by various stimuli, such as growth factors and inflammatory cytokines. Activated fibroblasts play a crucial role in wound healing, inflammation, formation of new blood vessels, and cancer progression. Uncontrolled activation of fibroblasts results in fibrosis, the excess deposition of fibrous tissue, which can lead to scarring and affect normal organs. This...
3.1K
Mitogens and the Cell Cycle
6.5K
Mitogens and their receptors play a crucial role in controlling the progression of the cell cycle. However, the loss of mitogenic control over cell division leads to tumor formation. Therefore, mitogens and mitogen receptors play an important role in cancer research. For instance, the epidermal growth factor (EGF) - a type of mitogen and its transmembrane receptor (EGFR), decides the fate of the cell's proliferation. When EGF binds to EGFR, a member of the ErbB family of tyrosine kinase...
6.5K
Targeted Cancer Therapies
7.6K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.6K
