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SPANN:注释单细胞分辨率的空间转录组数据与scRNA-seq数据

Musu Yuan1, Hui Wan2, Zihao Wang3

  • 1Center for Quantitative Biology, Peking University, Yiheyuan Road, 100871, Beijing, China.

Briefings in bioinformatics
|January 27, 2024
PubMed
概括

通过对齐单细胞RNA测序数据,SPANN准确地注释已知的细胞类型,并在空间转录组学数据中发现新的细胞,解决当前计算工具的局限性.

关键词:
单元格类型的注释最佳运输 (OT) 是指最优的运输方式.一个单细胞转录组的转录组.空间转录组空间转录组变化自编码器 (VAE) 的变化自编码器

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RNA-seq

RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
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