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在PD-L) 1和免疫疗法反应上WNT/β-catenin的调节作用

Keywan Mortezaee1

  • 1Department of Anatomy, School of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran. keywan987@yahoo.com.

Clinical and experimental medicine
|January 27, 2024
PubMed
概括

癌症中失调的WNT/β-catenin信号阻碍了抗瘤免疫力,并促进了对免疫检查点抑制剂 (ICI) 的抵抗力. 抑制这种途径可能会提高ICI治疗的疗效,以获得持久的抗瘤反应.

关键词:
免疫检查点抑制剂 (ICI)编程死亡-1 (PD-1) 是指编程死亡.编程死亡链条1 (PD-L1) 编程死亡链条1电阻 电阻 电阻 电阻 电阻 电阻瘤微环境 (TME) 是指瘤的微环境.这是一种β-catenin.

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