比利时癌症患者的营养不良患病率:ONCOCARE研究
Marika Rasschaert1, Pieter Vandecandelaere2, Stéphanie Marechal3
1Antwerp University Hospital, Antwerp, Belgium.
概括
晚期癌症患者中普遍存在营养不良和缓解症,这往往被医生低估. 早期营养评估和干预对于改善患者的治疗结果至关重要.
科学领域:
- 在瘤学瘤学.
- 临床营养学 临床营养学
- 流行病学 流行病学
背景情况:
- 在癌症患者中,无意减肥和营养不良很常见,会对生活质量,治疗耐受性和生存率产生负面影响.
- 关于比利时晚期癌症患者营养不良的流行病学数据有限.
研究的目的:
- 调查正在接受治疗的晚期癌症患者中营养不良,肉类和缓解症的患病率.
- 为了比较不同的营养不良评估工具,并评估营养支持.
主要方法:
- 一项前性观察性研究,涉及328名接受抗癌治疗的晚期癌症患者.
- 使用营养风险查评分2002 (NRS-2002) 和GLIM标准评估营养不良;用SARC-F查肉;用Fearon标准评估黄昏症.
- 在治疗开始后的基线,6周和4个月内收集的数据.
主要成果:
- 营养不良风险的高患病率 (在基线时为54.5%,在随访期间增加到70%以上) 和缓解症 (在基线时为38.1%).
- 营养不良和缓解症在医生主观评估 (PSA) 中被显著低估.
- 通过患者报告的食物摄入量检测到早期的营养缺陷,临床症状之前.
结论:
- 营养不良和缓解症非常普遍,并且在晚期癌症患者中经常被诊断不足.
- 严格和早期的营养评估,包括患者报告的摄入量,对于及时干预和改善临床结果至关重要.
- 调整营养摄入量可以积极影响癌症患者的管理.
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