血压暂时升高与心脏骤停风险增加有关
Yun Gi Kim1, Kyongjin Min2, Joo Hee Jeong1
1Division of Cardiology, Department of Internal Medicine, Korea University College of Medicine and Korea University Anam Hospital, 73 Goryeodae-Ro, Seongbuk-Gu, Seoul, 02841, Republic of Korea.
Scientific reports
|January 27, 2024
概括
血压上升的趋势显著增加了突然心脏骤停 (SCA) 的风险. 即使是压缩或压缩血压的小幅增加也与较高的SCA发生有关,而降低不会降低风险.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 高血压是突然心脏骤停 (SCA) 的已知的危险因素.
- 随着时间的推移,血压波动对SCA风险的影响仍然不清楚.
- 了解时间血压变化对于SCA预防策略至关重要.
研究的目的:
- 调查血压时间变化与突然心脏骤停 (SCA) 风险之间的关联.
- 为了确定血压上升或下降的趋势是否影响SCA发病率.
主要方法:
- 分析了2009年和2011年接受健康检查的个人的全国医疗保险数据.
- 在17740,420个人年的随访中,对8100个SCA事件的评估.
- 多变量分析以评估血压变化 (ΔSBP, ΔDBP) 与SCA风险之间的关系.
主要成果:
- 在缩血压 (SBP) 及时增加和SCA风险之间发现了线性关联.
- 较高的SBP增加 (例如,≥40 mmHg) 显示SCA的调整危险比率 (HR) 显著增加.
- 扩张性血压 (DBP) 的时间上升也与增加的SCA风险有显著的关联,特别是在最高 ΔDBP 组 (≥25 mmHg) 中.
结论:
- 血压的暂时升高,无论是静缩还是静缩,都与急性心脏骤停 (SCA) 的风险增加有关.
- 血压升高与SCA风险之间的关联在各个子组中一致,不论年龄,性别,糖尿病或基线血压.
- 预防血压升高可能是减少SCA发病率的关键策略;暂时降低血压不会减轻这种风险.
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