在患有恶性胆道阻塞的患者中,在EUS引导胆道排水后,肉症对复发性胆道阻塞的影响
Tomoya Emori1, Masahiro Itonaga2, Reiko Ashida2
1Department of Gastroenterology, Wakayama Rosai Hospital, 93-1 Kinomoto, Wakayama, 640-8505, Japan.
International journal of clinical oncology
|January 27, 2024
概括
肉,肌肉损失的条件,独立预测在内镜超声波引导胆道排水后不可切除的癌症患者的复发性胆道阻塞. 这一发现突出了萨科佩尼亚作为改善患者结果的关键预后因素.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 放射学 放射学是一门学科.
背景情况:
- 萨科佩尼亚是癌症患者的显著预后指标.
- 复发性胆道阻塞 (RBO) 是在不可切除的恶性胆道阻塞 (MBO) 中进行内镜超声引导胆道排水 (EUS-BD) 后的常见并发症.
研究的目的:
- 评估 Sarcopenia 在接受 EUS-BD 的 MBO 患者中对 RBO 的预测能力.
- 在EUS引导胆管排水 (EUS-BD) 后,确定肉症作为RBO的预后因素.
主要方法:
- 对113名MBO患者进行了自扩展金属支架 (SEMS) 的EUS-BD后期分析.
- 在第三腰椎水平 (L3) 的骨肌指数是从CT图像计算出来的.
- 使用单变量和多变量模型分析了累积发病率和RBO的时间.
主要成果:
- 与非sarcopenia组相比 (11%,p=0.034),sarcopenia组 (76名患者) 的180天累计RBO发病率 (29%) 显著更高.
- 萨科佩尼亚被确定为RBO的独立预测因子 (HR 4.61,p=0.001).
- 胆汁污泥/食物冲击是肉群中RBO的更常见原因 (p=0.048).
结论:
- 麻症是复发性胆道阻塞的独立预后因素,用于EUS-BD和SEMS治疗不可切除的恶性胆道阻塞的患者.
- 评估肉类可能有助于这些患者的风险分层和管理.
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