副首席调查员和HEAL-COVID试验:对实习生来说是好事,对试验来说是好事
Joseph Newman1,2, Philip Wild3,
1Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK. joseph.newman@nhs.net.
Trials
|January 27, 2024
概括
副首席研究员 (API) 计划有效地培训临床医生进行临床研究. 具有API的网站招募了超过3.5倍的患者,证明了该计划对试验效率和患者获取的影响.
科学领域:
- 临床研究 劳动力发展 劳动力发展
- 医疗保健服务研究 医疗服务研究
- 试用招聘策略 试用招聘策略
背景情况:
- 国家卫生研究院 (NIHR) 副首席研究员 (API) 计划于2020年在全国范围内实施,以培训临床医生成为未来的首席研究员.
- 紧急公共卫生研究HEAL-COVID适应性平台试验已在API计划中注册.
- 该试验在18个月内在100多个地点招募了近1200名患者.
研究的目的:
- 利用定性方法探索API计划对参与临床医生的专业发展的影响.
- 在HEAL-COVID试验中量化API对患者招募的贡献.
- 评估API计划在建设未来临床研究工作人员方面的有效性.
主要方法:
- 从应用数据分析API专业背景.
- 通过NIHR退出调查和反思实践练习来审查API经验.
- 对患者招募数据的多变量分析,比较具有和没有API的网站.
主要成果:
- 42个具有不同专业背景的API参与了HEAL-COVID试验.
- 拥有至少一个API的站点招募的患者数量超过没有API的站点的3.5倍 (中位数为14.5对4,p <0.05).
- 据报道,API完成了良好的临床实践培训,参与试验推广,并获得PI支持.
结论:
- NIHR API计划有效地提供研究培训,培养未来的临床研究工作人员.
- 在试验地点存在一种API,与患者招募率显著上升有关.
- 使用API计划注册试验可以提高试验效率,改善患者招募,并增加患者对研究的访问.
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