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在中国的唇部化品中的污染和致癌风险

Yu Gong^1,2, Junru Chu², Raymond Kwong³

¹Nanjing Institute of Environmental Sciences, Ministry of Ecology and Environment (MEE), Nanjing, 210042, P. R. China.

Bulletin of environmental contamination and toxicology

|January 28, 2024

概括

中国唇部化品中的 (Pb) 含量低于安全限值. 根据最近的安全评估,消费者对这些产品的暴露并不构成重大致癌风险.

科学领域:

环境健康环境健康
化品科学化品科学
毒理学毒理学毒理学

背景情况:

在全球范围内,人们越来越担心唇部化品中的 (Pb) 污染.
关于中国大嘴唇化品市场近期Pb污染和暴露风险的数据有限.

研究的目的:

测量中国流行唇部化品中的Pb含量.
评估与这些化品中的Pb暴露相关的致癌风险.
用生物可访问性纠正的风险评估和蒙特卡洛模拟来分析消费者Pb暴露.

主要方法:

在中国选取的29个唇部化品样本中分析Pb度.
使用生物可访问性校正计算增量终身癌症风险 (ILCR).
灵敏度和蒙特卡洛模拟用于可靠的暴露评估.

主要成果:

所有测试的唇部化品样本显示Pb度低于中国的监管限值 (10mg/kg).
测量到的Pb含量范围从无法检测到的 (<0.05μg/kg) 到0.21 mg/kg.
第50百分点的ILCR为1.20E-07,明显低于1E-06.6的可接受风险水平.

结论:

目前在中国的唇部化品通常符合Pb含量的安全标准.
由于这些唇部化品的典型使用,Pb暴露不太可能对消费者构成致癌风险.
该研究为了解和管理化品行业Pb风险提供了关键数据.

关键词:

致癌的风险致癌的风险评估健康风险评估健康风险领导领导领导领导领导唇部化品唇部化品

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