在晚期细胞癌患者的免疫检查点抑制剂基组疗法后,功能和结果之间的关联

Hiroki Ishihara1, Yuki Nemoto2, Hidekazu Tachibana3

  • 1Department of Urology, Tokyo Women's Medical University, Shinjuku-ku, Tokyo, Japan.

PubMed
概括

功能没有影响免疫检查点抑制剂 (ICI) 治疗在晚期癌中的有效性. 然而,安全性概况不同,IO-TKI组合显示慢性病 (CKD) 患者的不良事件增加.

相关概念视频

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Factors Affecting Renal Clearance: Renal Impairment

Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
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