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Tim J Evans¹, Megan C Romano²

¹Department of Biomedical Sciences, College of Veterinary Medicine, University of Missouri-Columbia, W226 Veterinary Medicine Building, 1520 Rollins Street, Columbia, MO 65211, USA.

The Veterinary clinics of North America. Equine practice

|January 28, 2024

概括

由真菌埃尔戈佩类类 (EPAs) 引起的马类埃尔戈佩类类毒性病 (EEPAT) 导致马匹具有相同的生殖问题,包括延长妊娠期和dystocia. 预防包括管理暴露和解决低分泌性血症.

科学领域:

兽医医学兽医医学兽医医学
毒理学毒理学毒理学
马类繁殖马类繁殖马类繁殖

背景情况:

体毒性和生殖性勃起症在孕母马中表现为类似的毒性症.
这些情况被统称为马类厄戈佩类化物毒性病 (EEPAT).
这两种综合征都源于真菌起源的埃尔戈佩类化物 (EPA).

研究的目的:

确定马类动物毒症和生殖性勃起症的常见原因和临床表现.
作为统一诊断,将马类埃尔戈佩类类毒性病 (EEPAT) 定义为一种统一诊断.
概述EEPAT的生殖后果和预防策略.

主要方法:

临床病例审查和对马匹暴露于埃尔戈佩醇化物 (EPA) 的毒理学分析.
对与高体内菌感染和Claviceps purpurea相关的毒性病的比较分析.
关于EEPAT病理生理学和临床症状的文献综合.

主要成果:

在孕期晚期的马匹中,EEPAT表现出相同的临床症状,包括因低蛋白质血症引起的角质变化/角质失调,妊娠延长和度变化.
从受影响的母马中出生的小经常表现出不成熟和被动转移的失败.
环保剂来源于高的Epichloë coenophiala或其他草的Claviceps purpurea.

结论:

由于真菌EPAs造成的EEPAT是马匹的一个显著的生殖危害.
有效的预防策略包括尽量减少接触受污染的料,并应对低菌性血症.
了解这些疾病的共同病因对于马匹生殖健康管理至关重要.

关键词:

一个galactia的动力.失星行为是指失星行为.迪斯托西亚 (Dystocia) 是一种表现不良的疾病.埃尔戈佩类类化合物埃尔戈佩类类化合物埃尔戈特已经得到了.埃尔戈特藻类的化物.爱尔哥主义 (Ergotism) 是一种对工作的热情.液中毒症液中毒症

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