关于影响低甲状腺症患者在不同环境中恢复的因素的后续研究
Si Wang1,2, Ping Chen3, Yayi He4
1Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, Shaanxi, China.
BMC endocrine disorders
|January 28, 2024
概括
状态可能不会直接影响甲状腺功能恢复在患有甲状腺功能低下的患者. 在这项为期6年的研究中,女性的性别和年龄的增加与较低的康复率有关.
科学领域:
- 内分泌学 在内分泌学.
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 自免疫性甲状腺疾病 (AITD) 通常表现为甲状腺功能低下症.
- 以前的研究将低 (Se) 状态与增加的甲状腺疾病患病率联系起来.
- 这项研究调查了Se状态是否影响甲状腺功能恢复在甲状腺功能下降患者.
研究的目的:
- 检查在患有亚临床或临床甲状腺功能低下症的患者中影响甲状腺功能恢复的因素.
- 具体评估 (Se) 状态在恢复甲状腺功能中的作用.
- 为了比较不同度Se的群体之间的康复率.
主要方法:
- 这是一项为期6年的前性队列研究,在两个具有不同Se级别的县进行.
- 从1,190个人收集的数据,包括人口统计,疾病和Se状态 (血清,指甲,尿道).
- 后勤回归分析以确定Se缺乏和甲状腺功能恢复之间的关联.
主要成果:
- 甲状腺功能恢复在Se缺乏县 (46.0%) 与Se充足县 (30.6%) 相比较高.
- 多变量分析发现女性的性别 (OR=1.875) 和年龄的增加 (OR=1.028) 与康复有负相关性.
- 在多变量分析中,Se状态和恢复之间的初始单变量关联消失了.
结论:
- 女性性别和晚年与30岁以上的甲状腺功能下降患者甲状腺功能恢复的不良结果有关.
- 状态对甲状腺功能恢复的直接影响需要进一步研究.
- 除了之外的因素,如性别和年龄,在恢复甲状腺功能方面发挥着重要作用.
相关概念视频
Synthesis and Regulation of Thyroid Hormones
4.6K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.6K
Functions of Thyroid Hormones
2.8K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
2.8K
Spermatogenesis
102.5K
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
102.5K
Major Hormones and Their Functions
394
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
394
Factors Affecting Body Temperature
4.2K
As a nurse, it is vital to understand the factors affecting body temperature to monitor variations and effectively evaluate deviations from regular.
Factors may include:
Factors may include:
4.2K
Minerals
309
Minerals are essential nutrients that the human body needs in small amounts to work properly. They play a vital role in many bodily functions, such as building strong bones and transmitting nerve impulses. Some minerals are needed for hormone production or to maintain a normal heartbeat. Major minerals include calcium, phosphorus, potassium, sulfur, sodium, chlorine, and magnesium, while trace minerals include iron, manganese, copper, iodine, zinc, cobalt, fluoride, and selenium.
Major...
Major...
309


