在体外生命支持期间治疗Candida auris:一个病例报告
Paul Dobry1,2, Stephanie B Edwin1, Tsz Hin Ng1
1Department of Pharmacy, Ascension St. John Hospital, Detroit, MI, USA.
The International journal of artificial organs
|January 28, 2024
概括
随着ECMO使用量的增加,鼻腔感染越来越令人担忧. 本案例研究详细介绍了使用组合抗真菌疗法治疗VV-ECMO患者的Candida auris感染的成功治疗方法.
科学领域:
- 传染性疾病 传染性疾病
- 菌类学 菌类学是指菌类学.
- 关键护理医学 关键护理医学
背景情况:
- 越来越多地利用体外膜氧化 (ECMO) 需要严格的感染预防协议.
- 黄菌是一种多药耐药的真菌,由于环境持久性,诊断困难和高死亡率,它带来了重大挑战.
- 鼻腔菌感染,特别是C. auris,在重症监护机构中构成了极大的威胁.
研究的目的:
- 在接受毒性体外膜氧化 (VV-ECMO) 的患者中报告Candida auris感染病例.
- 描述这种具有挑战性的真菌感染的成功管理策略.
- 突出有效的抗真菌治疗在ECMO免疫功能低下的患者的重要性.
主要方法:
- 一个VV-ECMO患者被诊断出患有Candida auris感染的病例报告.
- 治疗涉及一种组合抗真菌疗法,包括anidulafungin,amphotericin B和flucytosine.
- 在整个治疗过程中,对临床和微生物学结果进行了监测.
主要成果:
- 在VV-ECMO患者中成功管理Candida auris感染.
- 组合抗真菌疗法在清除真菌负担方面表现出有效性.
- 随着实施的治疗策略,患者的临床状况得到改善.
结论:
- 安尼杜拉金,安福特素B和流动的组合可以有效治疗VV-ECMO患者的Candida auris感染.
- 警监测和及时,积极的抗真菌疗法对于在重症患者中管理侵入性真菌感染至关重要.
- 这一案例强调了对新出现的多药耐药性真菌病原体的认识和量身定制的治疗方法的需要.
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