Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Pharmacovigilance01:19

Pharmacovigilance

833
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
833
Errors occurring during blood pressure monitoring01:25

Errors occurring during blood pressure monitoring

727
Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
Several factors...
727
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

698
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
698
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants01:18

Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants

1.2K
Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
1.2K
Guidelines for Nursing Documentation I01:30

Guidelines for Nursing Documentation I

1.1K
Quality documentation and reporting share essential characteristics that ensure they are practical and valuable resources for those who use them. These characteristics are:
Factual:  
The following points emphasize the significance of upholding accurate and unbiased documentation in healthcare.
1.1K
Guidelines and Strategies for Safe Computer Charting01:18

Guidelines and Strategies for Safe Computer Charting

806
The guidelines and strategies provided by the American Nurses Association (ANA) and the Canadian Nurses Association (CNA) offer essential principles for ensuring safe and secure computer charting systems in healthcare settings. Let's break down each recommendation:
Maintain Confidentiality and Security:
806

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Literature-based case analysis of serious adverse drug events associated with edoxaban.

European journal of clinical pharmacology·2025
Same author

Fatal adverse events of rivaroxaban combined with aspirin: an analysis using data from VigiBase.

European journal of clinical pharmacology·2022
Same author

Montelukast and Nightmares: Further Characterisation Using Data from VigiBase.

Drug safety·2022
Same author

Indapamide-Induced Rhabdomyolysis: An Evaluation of Case Reports in VigiBase Using the Bradford Hill Criteria.

Drugs - real world outcomes·2022
Same author

The International Society of Pharmacovigilance (ISoP) Pharmacogenomic Special Interest Group: Pharmacogenomics in Pharmacovigilance.

Drug safety·2021
Same author

Vaccination against COVID-19: insight from arterial and venous thrombosis occurrence using data from VigiBase.

The European respiratory journal·2021

相关实验视频

Updated: Jul 4, 2025

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
10:26

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

17.2K

与达比加特兰相关的严重药物错误:使用VigiBase数据进行分析.

Qingxia Zhang1, Qian Ding2, Qun-Ying Yue3

  • 1Department of Pharmacy, National Clinical Research Center for Geriatric Disease, Xuanwu Hospital Capital Medical University, Beijing, China. WL7322681@sina.com.

European journal of clinical pharmacology
|January 28, 2024
PubMed
概括

严重的药物错误 (ME) 与达比加特兰经常发生在处方和管理期间,导致不良事件,如出血和缺血. 谨慎的剂量,患者的遵守和适当的储存对于防止伤害至关重要.

关键词:
达比格拉特兰 (Dabigatran) 是一个名字.剂量错误是因为剂量错误.药物相互作用 药物相互作用药物错误是因为药物错误.严重 严重 严重这是VigiBase的数据库.

更多相关视频

Improving IV Insulin Administration in a Community Hospital
12:08

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

18.8K
Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
06:55

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

14.5K

相关实验视频

Last Updated: Jul 4, 2025

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
10:26

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

17.2K
Improving IV Insulin Administration in a Community Hospital
12:08

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

18.8K
Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
06:55

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

14.5K

科学领域:

  • 药物监督 药物监督 药物监督
  • 药品安全 药品安全
  • 临床药房 临床药房

背景情况:

  • 达比加特兰是一种抗凝剂,用于预防中风和血栓.
  • 药物错误 (ME) 可以导致严重的不良事件.
  • 分析ME对于提高患者安全至关重要.

研究的目的:

  • 分析与达比加特兰相关的严重药物错误.
  • 确定导致这些中小企业的因素.
  • 为预防不良事件提供见解.

主要方法:

  • 涉及达比加特兰的严重ME从世卫组织的VigiBase中提取出来.
  • 分析包括了经过充分记录的报告,vigiGrade分数≥0.80.
  • 使用了与毒品有关的问题的PCNE分类 (DRP).

主要成果:

  • 分析了113起经过充分记录的严重ME,其中61%导致住院,11%导致死亡.
  • 处方错误 (77例) 包括药物选择 (禁忌,相互作用) 和剂量问题.
  • 管理错误 (35例) 涉及医务人员和患者相关问题,主要不良事件是出血和缺血.

结论:

  • 严重的ME与达比加特兰主要发生在处方和管理期间.
  • 确保对正确的患者进行正确的剂量选择至关重要.
  • 在服用药物时,患者的坚持和适当的药物储存至关重要,以最大限度地减少危害.