在研究中报告SOFA:我们应该始终呈现每一个SOFA子记号
Zbigniew Putowski1, Marcelina Czok1, Kamil Polok2
1Centre for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, Kraków, Poland.
Anaesthesiology intensive therapy
|January 29, 2024
概括
顺序性器官衰竭评估 (SOFA) 的得分.
科学领域:
- 关键护理医学 关键护理医学
- 临床研究 临床研究
- 流行病学 流行病学
背景情况:
- 序列器官衰竭评估 (SOFA) 评分是广泛用于评估重症患者器官功能障碍的工具.
- 总的SOFA分数可能无法完全捕捉个体器官系统功能障碍的严重程度.
- SOFA分数通常用于预测死亡率.
研究的目的:
- 重新分析两组重症老年患者,比较COVID-19和非COVID-19病例.
- 探索SOFA分支的分布,并评估组间的差异.
- 为了评估个别SOFA分数与研究总分的实用性.
主要方法:
- 对两个队列的回顾性分析:910名非COVID-19和551名COVID-19患者.
- 队列根据年龄和入院的主要呼吸道原因进行了匹配.
- 总SOFA分数和个别SOFA分数 (呼吸,神经,心血管,凝血,,肝) 的比较.
主要成果:
- 在COVID-19和非COVID-19队列 (中位数5) 中,总SOFA分数与COVID-19队列相似.
- 在四个SOFA分值中观察到显著差异:呼吸,神经,心血管和凝血.
- 器官衰竭的比例 (SOFA子评分≥3) 在各组之间有所不同.
结论:
- 在COVID-19和非COVID-19呼吸道队列之间存在SOFA分数的显著差异.
- 仅仅依靠总的SOFA分数可能会掩盖器官功能障碍中的关键差异.
- 在临床研究中,个别的SOFA亚值对于准确报告器官功能障碍至关重要.
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