粘菌病:细针吸收细胞学中的细胞形态谱
Malvika Shastri1, Radhika Srinivasan1, Reetu Kundu1
1Department of Cytology and Gynecological Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Journal of cytology
|January 29, 2024
概括
精细针吸收细胞学 (FNAC) 能够有效地诊断各种器官的严重真菌感染 - - 粘真菌菌. 这项研究详细介绍了细胞形态特征,有助于及时启动治疗.
科学领域:
- 医学真菌学 医学真菌学
- 诊断细胞病理学诊断细胞病理学
背景情况:
- 粘菌菌是一种严重的侵入性真菌感染,具有显著的发病率和死亡率.
- 细针吸收细胞学 (FNAC) 对于粘膜菌的诊断实用性没有得到广泛的记录.
研究的目的:
- 为了阐明FNAC样本中粘菌菌病的详细细胞形态学特征.
- 为了将细胞形态学发现与临床和微生物学数据相关联.
主要方法:
- 对83例被诊断患有粘膜菌的FNAC病例 (2014年1月 - 2021年7月) 的回顾性分析.
- 评估细胞形态学,包括真菌元素和组织反应.
- 与临床数据和微生物学研究的相关性,如果有.
主要成果:
- 广泛的,非七面体的,带状的真菌菌株与直角分支是特征性的发现.
- 主要的组织反应包括死体炎症和平淡的死体模式.
- 免疫功能低下的患者更频繁地表现出混合的炎症反应.
结论:
- FNAC提供了一种快速而确的方法,用于从不同解剖位置诊断粘性肌病.
- 通过FNAC进行早期诊断有助于迅速进行治疗干预.
- 在FNAC中的组织反应可能是可变的,并受患者的免疫状况的影响.
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