高血压对风湿性关节炎患者骨矿物质密度的影响
Praveen Pratap Jadhav1, Vivek Gajanan Patwardhan2
1Omkar Rheumatology Clinic, Gaikwad Mala, Nashik, India.
Mediterranean journal of rheumatology
|January 29, 2024
概括
类风湿性关节炎 (RA) 患者的高血压 (HT) 可能会改善骨矿物质密度 (BMD) 与单独的RA相比,但仍然低于健康个体. 建议在RA患者的BMD解释时谨慎.
科学领域:
- 类风湿病学 类风湿病学
- 内分泌学 在内分泌学.
- 骨的新陈代谢 骨的新陈代谢
背景情况:
- 类风湿性关节炎 (RA) 与骨矿物质密度 (BMD) 的降低有关.
- 慢性疾病如II型糖尿病和高血压 (HT) 可以影响RA患者的BMD.
- 在新诊断的RA患者中,同时存在的HT对BMD的影响需要进行研究.
研究的目的:
- 确定高血压 (HT) 是否影响新诊断为类风湿性关节炎 (RA) 的患者的骨矿物质密度 (BMD) 参数.
主要方法:
- 分析了接受 BMD 评估的 RA 患者的研究群体.
- 患者被分为有HT和没有HT的组,以及健康的对照组.
- 使用GE Lunar DPX机器测量骨矿物质密度 (BMD),记录脊柱,大腿和全大腿的平均T分数.
主要成果:
- 年龄反向相关,而身体质量指数 (BMI) 与所有组的BMDT分数直接相关.
- 患有HT的RA患者的BMD比仅患有RA的患者高,但BMD比健康对照患者低.
- 多重回归分析表明,单独的BMI无法解释RA患者HT中观察到的T-分数升高.
结论:
- 在类风湿性关节炎 (RA) 患者中,高血压 (HT) 的存在似乎可以抵消RA的骨损伤作用,正如骨密度计所示.
- 对于具有同时存在HT的RA患者的骨矿物质密度 (BMD) 报告,应仔细考虑这种并发症.
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