饮食炎症指数和精神障碍之间的关联使用多层次建模使用GLIMMIX
Reza Beiranvand1, Mohammad Ali Mansournia1, Farhad Vahid2
1Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
较高的饮食炎症指数 (DII) 分数与增加的抑郁,焦虑和压力有关. 减少促炎食物可能会改善心理健康结果.
科学领域:
- 营养科学 营养科学
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 饮食炎症指数 (DII) 是一种被公认的衡量饮食炎症潜力的指标.
- 以前的研究表明,饮食和精神健康之间存在联系,但确切的关联需要对饮食成分进行调整.
- 多层次建模提供了一个强大的方法来分析复杂的营养数据和减轻偏差.
研究的目的:
- 调查饮食炎症指数 (DII) 与精神障碍,特别是抑郁,焦虑和压力之间的关联.
- 应用多层次建模来解释饮食数据 (食物,营养素,DII) 的等级结构.
- 为支持心理健康的饮食模式提供基于证据的建议.
主要方法:
- 一项采用德黑兰医学科学大学员工队列研究 (TEC) 数据的横截面分析研究.
- 通过半定量食品频率问卷 (DFQ) 评估的饮食摄入量.
- 心理健康状况使用抑郁,焦虑和压力表 (DASS-42) 进行评估.
- 在食品,营养素和DII级别使用多级建模 (SAS中的GLIMMIX) 分析数据.
主要成果:
- 总共有3,501名参与者被纳入分析.
- 在DII得分和压力,焦虑和抑郁的平均得分之间观察到显著的积极关联.
- 每个单位的DII增加与压力增加3.55,焦虑增加4.26,抑郁增加3.02相关 (p < 0.001).
结论:
- 建议减少对促炎性营养素和食物的摄入,以改善心理健康.
- 多层次数据分析对于在使用嵌套数据的营养研究中获得准确估计至关重要.
- 研究结果强调了饮食选择在管理和预防心理健康障碍方面的重要性.
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